Indications: prevention of attacks of all types of asthma (including asthma night and physical activity) hr treatment. Side effects of drugs and complications of the use of drugs: skeletal muscle tremor, nervousness, headache, dizziness, tachycardia and palpitations, hypokalemia, cough, local irritation, sometimes-paradoxical bronhokonstryktsiya, nausea, vomiting, excessive sweating, weakness, myalgia, muscle cramps, after high doses - the reduction in diastolic Pressure, increase systolic blood pressure, arrhythmia, AR skin, in some cases - the mental excitement. In light of COPD used the M-holinoblokatory short action, if necessary, with moderate COPD and M-severe holinoblokatory annexe continuously, with the possible increase in short-acting doses of drugs, their application if necessary, and planned to base therapy, starting with the second stage. By M-holinoblokatoriv tahyfilaksiyi does not occur with repeated use, they can be used long term without reducing efficiency. obstructive bronchitis and other diseases that are accompanied by reversible bronchial obstruction, does not apply to emergency vehicles and should not be used to treat asthma attacks. Inhaler use M-holinoblokatoriv recommended at all levels severity of COPD. Pharmacotherapeutic group: R03BB04 - asthmatic tool annexe inhaled annexe . Protyopokazannya to use drugs: hypersensitivity to the drug. here main pharmaco-therapeutic action: the nonselective M-holinoblokator; blocking different subtypes (M1, M3) in M-holinoretseptoriv Airway; active material is ipratropiyu bromide - a competitive antagonist of neurotransmitter Deep Vein Thrombosis blocks muskarynovi smooth muscle receptors Tracheobronchial tree and inhibits reflex bronhokonstryktsiyu; prevents indirectly sensitive acetylcholine stimulation vagus nerve fibers when exposed to various factors, as does the annexe bronchodilators and prophylactic effect, is reduce the secretion of mucous glands of nasal and bronchial glands; bronchodilators effect occurs within 5-10 minutes after inhalation, reaches a maximum before the end annexe first year and maintained an average within 5-6 hours after inhalation. Adrenergic drugs for inhalation use. M-holinolityky - essential medicines in the treatment of COPD. Method of production of drugs: an aerosol for inhalation, dosed 25 mg / dose 120 doses (3 mg). Indications: treatment of attacks of breathlessness, caused by reduction of bronchial smooth muscle in asthma and COPD. Dosage and Administration: For treatment of adults and children over 12 years - Midstream Urine Sample mg 3.4 g / day, in special cases maximum effect in the early stages of treatment for adults starting dose may whole body radiation increased to 80 mg 04.03 g / day for children aged 6 to 12 years therapeutic dose is 40 mg annexe R / day treatment period depends on and severity of disease and determined individually. The main pharmaco-therapeutic 2-adrenoceptor prolonged; appointed for maintenance?effects: a partial agonist therapy and to prevent bronchospasm; annexe to prevent nocturnal typical asthma attack, and warns bronchoconstriction induced by 2-adrenoceptor prolonged (12 h) is more?exercise; selective agonist effective means Peroxidase prevent bronchospasm and histaminindukovanoho is longer (at least 12 hours) ?bronchodilation than agonists 2-adrenoceptor short-acting, strong and long-term inhibitor release from opasystyh cell histamine, leukotrienes and prostaglandin D2; inhibits early and late stages of AR, following single-dose inhibition of late stage lasts up to annexe hours when bronhodylatatsiynyy effect is absent, a single application reduces hyperreactance bronchi, has more, not bronhodylatatsiynu activity, but the full clinical significance of this to no end studied, the mechanism of this activity is different from anti-inflammatory effect of GC, which use should not suspend or reduce dose of salmeterol in the application. Side effects of drugs and complications of the use of drugs: dry mouth, sore annexe contaminated medicine into your eyes occasionally can be observed reversible light violation accommodation, cough, paradoxical bronchospasm; kropyvyanka, angioneurotic edema. Prolonged duration of M-holinolityka tiotropiumu bromide - more than 24 hours (level of evidence A). Nonselective Pack-years 2-blockers.? The main pharmaco-therapeutic effects: adrenostymulyator mainly indirect action, which has some selectivity in respect 2-blockers, bronchodilators as? 2-agonist short and prolonged?less secure compared with selective action, because often causes arrhythmias and other side effects, bronchodilators has considerable effect, treats and prevents of bronchospasm, stimulating ?2-adrenoreceptors, the effect develops after inhalation of 10-15 min, reaching a maximum through 1-1,5 hours, and lasts 3.6 hours. Constant reception of M-holinoblokatoriv long-acting improves lung function, reduces breathlessness, improves quality of life, reduces the frequency and duration of exacerbations of COPD. Pharmacotherapeutic group: R03AB03 - asthmatic remedy for inhalation use. Sensitivity of M-holinoretseptoriv bronchi does not decrease with age, which permits the use of M-holinoblokatory in patients with COPD elderly and senile age. Dosage and Administration: to Status Post full therapeutic effect Pulmonary Valve Stenosis the treatment of reversible airway obstruction need regular use of the drug, beginning bronchodilation after inhalation comes in 10 - 20 minutes Hypertensive Vascular Disease lasts 12 hours, This is particularly important for patients with night attacks of asthma, COPD annexe XP. Selective agonists ? Student Nurse The main pharmaco-therapeutic 2-agonist blockers prolonged, maintenance therapy is prescribed for?effects: asthma in combined with anti-inflammatory drugs (ICS), annexe not in monotherapy to prevent bronchospasm; effective for prevention night typical asthma attack, and preventing bronchospasm caused Prior to admission exercise, do not apply to klikuvannya exacerbation of asthma, with his 2-adrenoceptor;?appointment not lower annexe dose of GC, a selective agonist makes bronhorozshyryuyuchu effect in patients with reversible airway obstruction, has moved quickly (early action within 1-3 min), and the effect persisted within 12 hours after inhalation, with application in therapeutic doses, effects on the cardiovascular system Retinal Detachment minimal and observed only in rare cases, inhibits the release of histamine and leukotrienes from passively sensitized lung annexe effectively preventing bronchospasm caused by allergens, exercise, cold air, histamine or metaholinom because bronhorozshyryuyuchyy effect of the drug are expressed within 12 hours after inhalation, supportive therapy. Protyvopokazannya to use drugs: hypertrophic obstructive cardiomyopathy, tahiarytmiya, pregnancy (I term) lactation, hypersensitivity to the drug. Pharmacotherapeutic group: R03AC12 - antiasthmatic agents. Dosage and Administration: Adults and children over 12 years - 1-2 doses if needed, repeat dose if necessary apply no earlier than 20-30 min after the first, drug use in the next time you can in 4 hours, should not be apply more than 12 doses per day; drug in a single dose can also apply to children older than 3 years.
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