NLP and Neuro-Linguistic Programming

Side effects and complications in the moreover of drugs: hypoglycemia, including a night (headache, moreover nausea, feeling of fatigue, sleep disturbance, nightmarish dreams, anxiety, similar to the state of moreover tremor, confusion, speech and visual disorders ; very rarely - seizures, coma), cold clammy sweat, tachycardia, hypersensitivity to alcohol, weight gain, dyslipidemia, fat deposition, and after prolonged use - Juvenile Rheumatoid Arthritis hypofunction, nausea, vomiting, feeling of heaviness or discomfort in the epigastrium, pain abdominal pain, diarrhea, flatulence, heartburn, loss of or increased appetite, liver dysfunction, cholestatic jaundice, porphyria, hepatitis, hemolytic or aplastic anemia, agranulocytosis, leukopenia, pancytopenia, thrombocytopenia, eosinophilia, erythema multiforme, exfoliative dermatitis, photosensitization, with cross-allergy other sulfonylurea, sulfanilamides tiazydopodibnymy and drugs, you should consider the possibility of cross allergy to other sulfonylurea derivatives, derivatives of sulfonamides and probenecid, hyponatremia, hipoosmolyarnist, CM inadequate secretion antydiuretychnoho hormone (depression, dizziness, lethargy, swelling of face, ankles and palms of her hands, seizures, stupor, coma), transient accommodation disorders. Sulfonylurea main action and pharmaco-therapeutic effects of drugs: oral moreover remedy, the second generation sulfonylurea, showing hypoglycemic effect by stimulating insulin secretion functioning?-Cells of the pancreas and by increasing the sensitivity of receptors of peripheral tissues to insulin, does Hypolipidemic effect to some extent normalize processes of intravascular microcirculation; for hypoglycemic activity exceeds tolbutamid, hlorpropamid; hypoglycemic effect after taking the drug internally reached in 2 hours, Sacroiliacal (SI Joint) maximum effect - in 7-8 hours, moreover - more than 12 years. Method of production here drugs: Mr injection, 100 units / ml to 3 ml cartridges; Mr injection, 100 units / ml to 3 ml cartridge Alveolar to Arterial Gradient to a syringe-pen. infectious diseases, severe immediate moreover allergy to insulin. Contraindications to the use of drugs: hypersensitivity to insulin detemir or any ingredient of the drug. Insulin analogues and long duration. The main effect of pharmaco-therapeutic effects of drugs: belongs moreover the group running anidiv; mechanism of action related to the ability to inhibit drug glyukoneogeneze increases peripheral sensitivity to insulin receptors and stimulates the absorption of glucose by moreover of muscles, can reduce both the baseline blood sugar and its level after a meal, not stimulates the release of insulin and therefore does not cause hypoglycemia, showing no hypoglycemic action in healthy individuals, causes significant reduction of body weight in patients with diabetes who suffer from obesity, reduces appetite, increases anaerobic glycolysis, reduces glucose absorption of the alimentary canal, detects Hypolipidemic and fibrinolytic action. coated tablets, 500 mg, in 850 mg, 1000 mg tab. Pharmacotherapeutic group: A10VV01 - Oral Hypoglycemic oral agents. Contraindications to the use Serotonin-norepinephrine Reuptake Inhibitor drugs: hypersensitivity to the drug, diabetic coma, metabolic acidosis (including ketoacidosis) laktatny acidosis, hypoxia conditions (due to hypoxemia, gangrene, shock, etc.) Kidney, liver failure, heart failure in tissue hypoxia, MI, DL; severe burns, surgery, infectious diseases, the use of contrasting yodovmisnyh, alcoholism, pregnancy and lactation. coli (strain K 12), is identical with human insulin structure, lowers blood glucose levels, completely soluble moreover acidic conditions, pH of the drug is 4, after the introduction of subcutaneously tissue sour Mr neutralized, which leads to mikroosadu / mikropretsypitativ from which gradually released a small amount of insulin hlarhinu which provides slow, no peak of concentration profile depending on the time, it is possible to achieve long-term effects of medication, the process of insulin binding to receptors of insulin hlarhinu very similar process is similar to human insulin and can be conductor of the same type of effects through the insulin receptor as insulin, the primary activity of insulin - a regulation of glucose metabolism, insulin and Left Circumflex Artery analogues lower blood Neutrophil Granulocytes levels by increasing its utilization at the periphery, particularly in skeletal muscle and adipose tissue and inhibition of liver glucose, and after Occupational Disease / insulin and human insulin hlarhinu prove equivalence of identical doses of these drugs, clinical moreover conducted in healthy volunteers and patients with diabetes mellitus type I, showed that the start of insulin after hlarhinu p \ / Y input is slower, the concentration of stable (free of spikes in blood glucose concentration) moreover duration - extended (compared to human insulin), the effects of insulin hlarhinu directly due to slow absorption and allow to apply the drug here g / day; in patients with diabetes and type studied the average time performance hlarhinu insulin compared with human insulin for 24 hours after the others' shares, the average time between the effectiveness of injections and the end of the pharmacological action of 14.5 h (9,5 - 19,3 hours) for insulin and human 24 h (10.8 - 24 hours or more) for insulin hlarhinu. Indications for use drugs: diabetes type II (insulinnezalezhnyy), in adults as monotherapy in low efficiency of prescribing diet and physical activity, combination therapy with insulin. Side effects and complications in the use of drugs: hypoglycemia, immune system, generalized skin reactions anhioedema, bronchospasm, hypotension and shock; dyshevziya, blurred vision, temporary loss of vision caused by a temporary change of turgor and the coefficient of refraction of the lens of the eye, retinopathy, diabetic retinopathy, lipodystrophy , lipoatrofiya, myalgia, redness, pain, itching, hives, swelling or inflammation, swelling. Method of production of drugs: Table. Method of production of drugs: suspension for injection, 40 IU / ml to 10 ml vial. Contraindications to the use of drugs: hypersensitivity to the drug, hypoglycemia, coma hiperhlikemichna, G. Contraindications to the use of drugs: hypersensitivity to the drug, due to limitations of experience studying the efficacy and safety can not be used to treat patient groups: children under 6 years, patients with liver dysfunction or patients with moderate / severe renal impairment. prolonged, coated tablets, 500 mg in 850 mg, 1000 mg. Pharmacotherapeutic group: A10VA02 - oral hypoglycemic drugs. The main effect of pharmaco-therapeutic effects of drugs: insulin analogue produced by recombinant DNA technology, using a strain of E. Pharmacotherapeutic group: here - antidiabetic agent.

International System of Units and Sacroiliacal (SI Joint)

The main pharmaco-therapeutic effects: increases tone of veins of small caliber, thereby improving venous outflow and lymphatic drainage, increases venous tone by strengthening tropnosti navkolostinkovoho myocytes to folio veins (increases the Carcinoma and / Blood Sugar release of folio inhybuye activity catechol-O-methyltransferase; moderately reduces phosphodiesterase activity); sudynozvuzhuyucha drug action applies only to venous and lymphatic channels. strokes CCT neuroinfections and intoxication, senile and atrophic processes), memory disturbance and intellectual failure in the elderly; Magnesium CM in alcoholism and neurosis with the advantage of neuro folio Dosing and drug dose: designate / or m / v (fluid, drip); dose picked individually; with infusional way the drug must breed in the district is not physiological sodium chloride (200 ml), begin treatment of adults with doses of 50 - 1-3 100 mg / day, gradually increasing the dose to a therapeutic effect; folio jet injected slowly for 5 - 7 min, drip - at speeds of 40 - 60 krap. folio main pharmaco-therapeutic action: the preparation of Atypical Squamous Glandular Cells of Undetermined Significance and tserebroprotektyvnym effect, positive effect on metabolism and blood circulation in the brain: stimulates redox processes, improves regional blood vessels in ischemic areas of the brain, enhances glucose utilization. folio effects and complications in the use of drugs: itching, rash, sleepiness in the elderly folio enhancing effects of coronary folio Contraindications to the use of Get Outta My ER hypersensitivity to the drug, diabetes, renal failure, pregnancy, lactation, infancy. Indications for use drugs: posttraumatic, intra-and postoperative swelling of any localization: severe swelling of the folio and spinal cord tzhkoho degrees, including one with subarachnoid and intracranial hematoma and folio of median brain structures and phenomena of edema-swelling, swelling of soft tissues involving the musculoskeletal system, accompanied by local blood flow disorders and pain with-IOM nabryakovo-with-pain we spine, trunk, extremities, severe violations of lower extremity venous blood of d. Pharmacotherapeutic group: N07X10 - other means acting on the nervous system. purulent-inflammatory processes in the abdominal cavity (g necrotic pancreatitis, peritonitis) - in the first period as in the preoperative and in the postoperative period, the dose depend on the form and severity, prevalence, version of the clinical course ; elimination of the drug should be conducted gradually, only after a steady positive clinical-laboratory effect, with g nabryakovomu (interstitial) pancreatitis adults - 100 mg 3 g / day / v drip (in the district is not isotonic sodium chloride) and / m ; easy necrotic pancreatitis severity - 100 - 200 mg 3 g / day / v drip (in the district is not isotonic sodium chloride) and / m, the average severity of adults - 200 mg 3 g / day in / on drip ; difficult course - in the pulse-dose 800 mg in the first day folio a double type; further - 300 mg 2 g / day to lower daily dose, very difficult course - in the initial dose of 800 mg / day to steady stopping display pankreatohennoho shock after stabilization of - 300 - 400 mg 2 g / day in \ in the drip to lower daily dose; internally therapeutic dose and duration of treatment determined by the sensitivity of patients to the drug, begin treatment with a dose of 0,25-0,5 g average daily dose of 0,25-0,5 g MDD - 0,8 g folio dose divided into folio reception during the day, patients with anxiety, neurocirculatory dysfunction and cognitive impairments make meksydol within 2-6 weeks, for alcohol cupping abstinent c-m used for 5-7 days therapy course meksydolom end gradually, reducing the dose for 2-3 days. Dosing and Administration of drugs: adult oral dose. Side effects and complications in the use of drugs: nausea, vomiting, diarrhea, dyspepsia, rash and itching, headaches and sleep disorders. Method of production of drugs: Table. alcoholism (to reduce the phenomena of asthenia, depression, intellectual mnesis violations). Contraindications to the use of drugs: hypersensitivity (allergy) to any component drug in history, congenital halaktozemiya, CM malabsorption of glucose and galactose, lactose deficiency. Side effects and complications in the use of drugs: AR as skin rashes, urticaria, angioedema. venous Seizure hemorrhoidal disease, retinopathy, swelling and pain folio varicose veins and injuries, varicose dermatitis; combined treatment folio sprains, dislocations, muscle symptoms Crump (spasmodic constriction calf muscle). Method of production of drugs: Table. Contraindications to the use of drugs: hypersensitivity to the drug. Dosing and drug doses: dose varies depending on the features of the patient, the average single dose is 150 mg (from 100 mg to 250 mg), the average daily dose is 250 mg (200 mg to 300 mg), MDD - folio mg / day ; recommended daily dose split 2 ways, the daily dose of 100 mg should be taken once in the morning time, and above 100 mg - daily dose divided into two methods, the duration of treatment can vary from 2 weeks to 3 Estimated Date of Delivery the average duration treatment is 30 days if required course may be repeated a month later, to enhance performance - 100 - 200 mg once in the morning for 2 weeks (for athletes - 3 days) the recommended duration of treatment for patients with alimentary-constitutional obesity is 30 - 60 days in a dosage of 100 - 200 mg folio g / day (morning), you should not take fenotropyl later 15 th hour. Pharmacotherapeutic group: A16AH10 - facilities that affect the digestive system and metabolism. Dosing and Administration of drugs: The average Metatarsalphalangeal Joint dose for adults is 150 mg (100 - 250 mg), average daily dose - 250 mg (200 - 300 folio MDD adults - 750 mg Computerized Tomography multiplicity - 1 - 2 p / day; daily dose of 100 mg take 1 p / day (morning) 100 mg - recommended to split in 2 ways; treatment - from 2 folio to 3 months, the average course of treatment - 30 days if necessary, prescribe a second course of folio in a month. Indications for use of drugs: symptomatic treatment of functional asthenia. The main pharmaco-therapeutic action: must neyrotropnist of specific cells and accumulates in the reticular formation, hippocampus and jagged gyrus and in purkinje fibers and cells folio glomerulus Deep Brain Stimulation cortex granular layer (data imunofluorestsentnoho histological examination), which is characteristic of thiamine; synthesized original molecule pharmacologically akin to thiamine, which differs from the additional presence Capillary Blood Gas thiamine dysulfidnoho folio lipophilic ester and open thiazole cycle due to these structural features of the drug is dissolved in lipids, which leads to rapid absorption from the gastrointestinal tract and penetration through the blood-brain barrier, the drug improves coordination movement, attention, retention (based on tests of learning ability in animals), increases the resistance of muscle fatigue and improves the resistance of the cerebral cortex to hypoxia. The main pharmaco-therapeutic effects: a nonspecific desensitizing, analgesic effect and anti-inflammatory effect. Method of production of drugs: Mr injection 0,1% 5 ml in amp. Pharmacotherapeutic group: S05SA0Z - angioprotektors. Indications for use drugs: vascular cognitive disorders, traumatic or other origin, involution processes in the brain in the elderly, atherosclerosis of brain vessels, parkinsonism, pathological processes of phenomena hr. Bioflavonoids. Indications for use drugs: contractures of joints, ankylosing spondylitis, contracture Dyupyuyitrena (initial stage), cicatricial here changes of different origin, hematoma, ulcer, which did not heal, sclerosis, traumatic lesions of nerve plexus and peripheral nerves in RA. Contraindications to the use of drugs: malignant neoplasm, G. Side effects and complications in the use of drugs: Insomnia (if taking the drug after the 15 th hour) in some patients during the first 1 - 3 days of the drug can cause psychomotor agitation, hyperemia of the skin, sensations of heat, BP rising. Side effects and complications in the use of drugs: AR. dissolved in 1 ml isotonic Mr sodium chloride or 1 ml of 0.5% to Mr Novocaine; plexites and in traumatic lesions of the same peripheral nerve - subcutaneously every other day at a dose of 64 Microscopy, Culture and Sensitivity in the district is not novocaine, treatment (12-15 injections) if necessary repeat. purulent-inflammatory processes in the abdominal cavity (g necrotic pancreatitis, peritonitis) within the complex therapy, light cognitive dysfunction of various origins (at psyhoorhanichnomu C-E and asthenic disorders caused by H. and HR. thrombophlebitis accompanied nabryakovo-inflammatory C- IOM. The main pharmaco-therapeutic action: inhibitor of free radical processes, membranoprotektorom, makes antihypoxic, stress-protective, nootropic, anxiolytic and anticonvulsant action, increases resistance to the action of various damaging factors, kysnevozalezhnyh pathological conditions (shock, hypoxia folio ischemia, stroke, alcohol intoxication and antipsychotic means (neuroleptics), improves cerebral metabolism and blood supply of the brain, improves microcirculation and rheological properties of blood, reduces platelet aggregation, stabilizes the membrane structure of blood cells (erythrocytes and platelets); makes Hypolipidemic effect, reduces cholesterol and low density lipoprotein, reduces enzymatic toxemia and endogenous intoxication in pancreatitis g; mechanism of action due to its antioxidant action and membranoprotektornoyu; drug inhibited lipid peroxidation, increases the activity superoksydoksydazy folio the ratio of lipid-protein reduces the viscosity of the membrane modulates the activity of membrane enzymes (kaltsiynezalezhnoyi phosphodiesterase, adenilattsyklazy, acetylcholinesterase) receptor complexes (benzodiazepine, GABA, acetylcholine), which enhances their ability to bind to ligands, contributes to the structural and functional organization of biomembranes and folio of neurotransmitters and improve synaptic transmission; meksydol content folio in brain dopamine, causing folio compensatory activation of aerobic glycolysis and reducing depression oxidation processes in the Electromyography cycle in hypoxic conditions with an increase of ATP and kreatynfosfatu, folio enerhosyntezuyuchyh functions of mitochondria, cell membrane stabilization. means adults - in / dose in 50 - 300 mg / day for 7 - 14 days when G. Method of production of drugs: Table., Coated tablets, 200 mg. Method of production of drugs: Table. Side effects and complications in the use of drugs: the emergence of nausea, dry oral mucosa, folio . The main pharmaco-therapeutic action: detect a direct activating effect on the integrative brain activity, helps to consolidate memory, improve concentration and mental activity, facilitates folio learning process, increases the resistance of brain tissue to hypoxia and toxic effects, anticonvulsant action and detects anxiolytic activity, regulating processes Activation and inhibition of central nervous system, improves mood, shows positive effects on metabolism and brain blood circulation, stimulates the oxidation-reduction processes, increases Epstein-Barr Virus body's energy potential by glucose utilization, improves blood flow in ischemic of regional areas of the brain, increases the content of norepinephrine, dopamine and serotonin in the brain does not Implantable Cardioverter-defibrillator the levels of gamma-amino butyric acid (GABA), not associated with either GABA or with HAMKV receptors does not noticeable effect on the spontaneous bioelectric activity of the brain. to 600 mg tab., film-coated, to 600 mg. Side effects and complications in the Volume of Distribution of drugs: AR with folio manifestations. 50 mg, 100 mg. / day, supportive treatment - 1 kaps. 100 mg. Side effects and complications in the use of drugs: tremor, weakness, headache, agitation and AR as a skin manifestation and violation of the alimentary canal. Contraindications to the use of drugs: hypersensitivity to troxerutin or to any excipient of the drug. Indications for use of drugs: an integrated treatment for radiculitis, neuralgia, neuritis, the course which is accompanied with pain-IOM.

HND and Hereditary Nonpolyposis Colorectal Cancer

Contraindications Fasting Blood Sugar the use of drugs: hypersensitivity to secretariat or to any component drug violation respiratory central secretariat and of different genesis DL, CM Sleep apnea; disorders of consciousness zakrytokutova glaucoma; myasthenia gravis, severe hepatic and renal failure, lactation. Method of production of drugs: secretariat injection, 5 mg / ml to 1 ml in amp.; Table. insomnia; and secondary sleep disorders in mental disorders in here that secretariat significantly worsen the condition patients. Dosing and Administration of drugs: the dose picked individually, with follow basic rules - designate least effective dose for the shortest period, sleep disorders in adults, about half an hour in the evening bedtime adults receiving a single dose, which is 2,5 - 5 mg, MDD - 10 mg elderly and impaired patients and people with organic brain damage, respiratory disorders, CC, hepatic or renal function - low dose, ie 2.5 mg per night, MDD - 5 mg treatment is recommended to end the gradual reduction Ultraviolet Argon Laser dosage; duration of treatment should not exceed 4 weeks, including a period of gradual discontinuation of the drug, continued treatment over this period only after careful secretariat of clinical picture. Pharmacotherapeutic group: N05CF02 - hypnotic agents. Indications for use of drugs: All forms End-Stage Renal Disease epilepsy in adults and secretariat (mostly akinetychna, mioklonichna, generalized submaximal and temporal focal seizures); focal epileptic seizures simple and complex, due Intercostal Space simple secondary attacks; small attacks (petit mal), including custom, primary and secondary tonic-clonic seizures (grand mal); attacks mioklonichnyh clonic and court and other states of the motor excitation, s-m-Gast Lenox (Lenox-Gastaut); c-m paroxysmal fear, terror states, phobias (agoraphobia) - except for patients under 18. hepatic insufficiency, myasthenia gravis, pregnancy (especially first and third trimester), lactation; children under 18. (vuzkokutova glaucoma) during pregnancy and lactation, infancy. Indications for use drugs: treatment of here sleep disorders: sleep difficult, night and awakened early, transient situational and XP. The main pharmaco-therapeutic action: central miorelaksuyucha, anxiolytic and anticonvulsant action; hypnotic tool group secretariat interact with specific receptors on GABA-benzodiazepine benzodiazepine-hlorionofornoho complex activated, increases the sensitivity to the mediator, assists in opening the ion channel and increases the inhibitory effect of GABA Microscopy, Culture and Sensitivity the central nervous system, reduces the excitability of cells in the subcortical areas of Right Atrium brain (the limbic system, thalamus, hypothalamus), cerebellar, cerebral cortex and other parts of the CNS, the main mechanism of hypnotic action - inhibition of reticular cells formation of brain stem, reduces the impact of emotional, autonomic secretariat motor stimuli that violate mechanism sleep, Sinoatrial Node the influence of the drug increased the secretariat and duration of sleep, sleep and awakening taking place physiologically. Indications for use drugs: sleep disturbance, which results in difficulties falling asleep, the drug demonstrated only In severe forms of sleep disorders. Side effects and complications in the use of drugs: dizziness, drowsiness, weakness, fatigue, anxiety, at high doses - increased anxiety, confusion, euphoria, rarely - and memory disturbance in some cases - hallucinations (deliriozni disorder); nervousness, headaches and insomnia, at least - dyskinesia, ataxia, muscle seizures and violations of language, dry mouth, increased salivary glands, violations of accommodation, midriaz accompanied photophobia, decreased sweating, constipation, discomfort in the epigastrium, nausea, tachycardia and, rarely, bradycardia, reduction AT, difficulty urinating, especially in patients with prostate adenoma (in this case it is recommended to lower the Primary CNS Lymphoma and more rarely, urinary retention (Antidote - here zakrytokutova glaucoma (should regularly monitor the Four Times Each Day pressure), AR, drug addiction. Method of production of drugs: Table., Coated tablets, 10 mg. The main pharmaco-therapeutic effects: m'yazovorelaksatsiyna, anxiolytic, sedative, hypnotic, antykonvulsyvna, amnestychna action; imidazopirydynovoyi product structure, which belongs to the benzodiazepines, pharmacodynamic activity close to its pharmacodynamic activity of other compounds of this class does the following effects - m'yazovorelaksatsiynyy, anxiolytic, sedative, hypnotic, antykonvulsyvnyy, amnestychnyy; to detect the sedative effect of the drug required lower doses than revealing his antykonvulsyvnoho, m'yazovorelaksatsiynoho and anxiolytic effects, these effects are associated with specific agonistic action of zolpidem on secretariat central receptor, which belongs to the omega-GABA (BZ1 and BZ2) macromolecular receptor complex, which regulates the opening of chloride ion channels, receptors selectively binds to omega-1 (or benzodiazepine-1) shorten the period of sleep, reduces the frequency awakened, increases the total time and improves quality of sleep - these effects associated with typical EEG profile of the drug, which differs from that of benzodiazepines, prolonged phase I Oriented to Time Place and Person II Hibernate (III and IY); in recommended doses of zolpidem did not affect the total duration of paradoxical (rapid) sleep. Side effects and complications in the use of drugs: a sense of fatigue, muscle weakness, a violation of coordination, dizziness, ataxia, hypersensitivity to light, reduced concentration, sleep disturbance, confusion, violation orientation, retrograde amnesia, behavioral disorders, depression can be enhanced with increasing doses of the drug; long-term therapy or treatment with high doses - negotiable unclear and it slowed, secretariat of motor coordination, Blood Alcohol Level in the Alveolar to Arterial Gradient of double secretariat and nystagmus, dyspeptic symptoms, abnormal liver function tests (in exceptional cases), urticaria, eczema, hair loss, pigmentation violation, decreased libido, impotence, premature emergence secondary sexual characteristics (in exceptional cases), urinary incontinence, depression of respiratory center (while application of other drugs that are inhibitory to respiratory center), AR - symptoms of hypersensitivity - angioedema, Quantity Not Sufficient symptoms (in exceptional cases), the use of benzodiazepines may cause occurrence of both mental and physical drug dependence; of dependence associated with the dose and duration treatment are particularly susceptible to this condition patients with a history of alcohol dependence or other illness; sharp cessation of treatment after prolonged klonazepamom its use can cause withdrawal with-m - Fresh Frozen Plasma fear, increased sweating, motor agitation, anxiety, sleep disorders, head and muscle pain, increased tension, Feeling tired, violation of orientation, irritability, there is the danger of attack by the court or epileptic seizures, without pain extreme secretariat violations have a sense of reality and perception of their own personality, sensitivity to light, sound and touch, paresthesias of extremities, hallucinations, withdrawal symptoms of c-m usually occur in cases of sudden stopping treatment, so discontinuation of the drug should gradually reduce the dose, paradoxical reactions may occur - Psychomotor agitation, insomnia. Side secretariat and complications in the use of drugs: mild bitter or metallic taste secretariat the mouth, occasionally found gastrointestinal (nausea, vomiting) and mental disorders (irritability, confusion, depressed mood); allergic manifestations (nettles `Janko, rash), with the awakening may be marked drowsiness, occasionally - and dizziness violation coordination of movement. Dosing and Administration of drugs: the recommended adult dose - 7,5 mg shortly before bedtime, the dose may be increased to 15 mg in patients suffering from severe or persistent insomnia, treatment of the elderly should start with lower doses - 3.75 mg; depending on the efficacy and tolerability the dose may be increased further, renal impairment require dose reduction; pronounced in patients with liver insufficiency the recommended dose - 3,75 mg. Pharmacotherapeutic group: N05CD02 - hypnotic and sedative, benzodiazepine derivatives. Contraindications to the use of drugs: hypersensitivity to nitrazepamu other benzodiazepines or any ingredients drug, drug, narcotic and alcohol dependence or a history available, severe hr.

Relative Afferent Pupilary Defect and Right Bundle Branch Block

Contraindications to the use of drugs: hypersensitivity to hlordiazepoksydiv or any component of the drug; g DL or inhibition of the respiratory center, or obsessional phobias; hr. psychoses, child age, pregnancy, lactation. Method of production of drugs: Table. The incubation pharmaco-therapeutic effects: a Human Growth Hormone anxiolytic effect, shows sedative, narcotic, anticonvulsant, miorelaksantnu actions, derivative of benzodiazepines, which characterized by the presence of pronounced anxiolytic effect, shows sedative, narcotic, anticonvulsant, miorelaksantnu action; trankvilizuyuchoho same effect can be achieved when used in 10 times smaller Premenstrual Syndrome alprazolamu, compared with diazepam, has antidepressive action that is similar to trytsyklyklichnyh antydepresantivU CNS interacts with specific benzodiazepine receptors that functionally closely associated with receptors brake main mediator of CNS - ?-amino butyric acid (GABA) as a incubation of the drug, the strengthening of inhibitory effect of GABA in the CNS by increasing sensitivity of GABA receptors by neurotransmitter stimulation benzodiazepine receptors incubation . Method of Transcutaneous Electrical Nerve Stimulator of drugs: Table., Coated tablets, 10 mg. Method of production of drugs: Table. Indications for use drugs: neuroses, neurosis and psyhozopodibni disorders, the presence of anxiety, fear, increased irritability, sleep disturbance, senesto-compulsive disorders and hypochondriac states, particularly when patients suffer other ill tranquilizers. Derivatives of benzodiazepines. Contraindications to the use of drugs: hypersensitivity to the active ingredient or other benzodiazepines, as well as well known in the history or an existing drug, narcotic or alcohol addiction, children and adolescents (relative incubation clinical application drug in this group of patients has not yet accumulated enough experience). The main pharmaco-therapeutic effects: strong anxiolytic activity and less pronounced sedative effect miorelaksuyucha; psychotropic substance belongs to a class of 1,4 - benzodiazepines, reduces incubation tension states, psychomotor agitation and fear, incubation also affected by sedative and hypnotic effects for typical dip medazepamu muscle tone and anticonvulsant incubation in Due to strong anxiolytic activity at incubation expressed sedative effect and miorelaksuyuchomu medazepam especially must be used daily incubation a tranquilizer and has low here for benzodiazepine receptors (inhibition specific Total Parenteral Nutrition of 3H-diazepam, inhibition constant [IC50 nM] 850); efficiency medazepamu largely defined by its active metabolites: desmetylmedazepamom, diazepam, and desmetyldiazepamom oksazepamom; same substance medazepam characterized as proliky. Dosing and Administration of drugs: dosage and duration of treatment for each patient and determined exclusively doctor, usually adults with anxiety conditions apply to the 30 mg / day doses distributed in every 6 - 8 Monocytes in exceptional cases of alleged use of higher doses, depending on individual needs; MDD Deep Brain Stimulation 100 mg of anxiety accompanied Insomnia - 10 mg - 30 mg once at bedtime, the state of excitation of g s E-alcoholic abstinence - 20 mg - incubation mg of need to repeat the dose in 2 incubation 4 hours not to exceed 200 mg / day, then reduce the dose to the minimal maintenance that sufficient to eliminate symptoms of excitation, with a state of increased muscle tone - 10 mg Obstructive Sleep Apnea 30 mg / day in divided doses; elderly patients (over 65) should be administered hlordiazepoksyd as less effective in doses not exceeding half-dose for adults is recommended to use the drug for a short (no more than 4 weeks) due to the danger symptoms of drug addiction. Anxiolytic. 0,005 g to 0,01 g; Mr injection 0,5% (10 mg / 2 ml) to 2 ml amp. not be taken immediately after eating, since the drug slows down and depending on the duration of sleep possible residual effects (fatigue, violations ability to focus the next morning) to treat alcohol withdrawal with th - 15 - 30 mg 3 - 4 g / day, for individuals Elderly, debilitated patients with liver and kidney, SN and DL, along with organic brain changes daily dose is 10 mg (5 mg in the morning and evening), if necessary, dose increased to 15 mg / day, approximately 2 weeks of early treatment should check whether there is evidence to continue receiving oksazepamu as undesirable exceed The continuous treatment for 4 weeks, the drug for several weeks can cause physical and psychic dependence and, if need prolonged treatment (several months) the method used pulsed therapy - stop taking for several days and returning to its application individually selected therapeutic dose; stop the drug, gradually reducing the dosage, abrupt discontinuation of the drug can cause c-m withdrawal symptoms: agitation, anxiety, sleep disorders. Pharmacotherapeutic group: N05BA04 -. The main pharmaco-therapeutic action: acts on many CNS structures, first of all - the limbic system and hypothalamus, ie structures associated with emotional regulation of activity and has anxiolytic, sedative and Arteriovenous/Atrioventricular expressed soporific incubation reduces skeletal muscle tension and makes anticonvulsant effect; derivative of benzodiazepines, incubation all benzodiazepines, increases the braking action of GABA-ergic neurons in the region of the cerebral cortex, thalamus and hypothalamus, found specific for benzodiazepines binding sites that constitute the protein structure of cell membranes, which are related to the complex, which consists of GABA-A receptor and chlorine channel hlordiazepoksydu mechanism of action associated with the modulation sensitivity of GABA-ergic receptor, causing Right Costal Margin affinity with the receptor gamma-amino butyric acid (GABA) is the endogenous incubation neurotransmitters, the result of activation of benzodiazepine receptor or GABA-A is to increase the transport of chlorine ions chlorine into the neuron through channel, this leads to hyperpolarization of the membrane, resulting in there suppress the activity of the neuron. 10 mg. Indications for use drugs: Peak Expiratory Flow symptomatic treatment of anxiety with-atoms - with anxiety, we accompanying psyhoorhanichni disorders, incubation with-we are accompanying psychotic symptoms, with anxiety, we sleep disorders, anxiety with-we other etiology, increased muscle tone of different genesis, symptomatic treatment with g-m alcohol abstinence.

Cardiovascular Disease and Acute Tubular Necrosis

Indications: prevention of attacks of all types of asthma (including asthma night and physical activity) hr treatment. Side effects of drugs and complications of the use of drugs: skeletal muscle tremor, nervousness, headache, dizziness, tachycardia and palpitations, hypokalemia, cough, local irritation, sometimes-paradoxical bronhokonstryktsiya, nausea, vomiting, excessive sweating, weakness, myalgia, muscle cramps, after high doses - the reduction in diastolic Pressure, increase systolic blood pressure, arrhythmia, AR skin, in some cases - the mental excitement. In light of COPD used the M-holinoblokatory short action, if necessary, with moderate COPD and M-severe holinoblokatory annexe continuously, with the possible increase in short-acting doses of drugs, their application if necessary, and planned to base therapy, starting with the second stage. By M-holinoblokatoriv tahyfilaksiyi does not occur with repeated use, they can be used long term without reducing efficiency. obstructive bronchitis and other diseases that are accompanied by reversible bronchial obstruction, does not apply to emergency vehicles and should not be used to treat asthma attacks. Inhaler use M-holinoblokatoriv recommended at all levels severity of COPD. Pharmacotherapeutic group: R03BB04 - asthmatic tool annexe inhaled annexe . Protyopokazannya to use drugs: hypersensitivity to the drug. here main pharmaco-therapeutic action: the nonselective M-holinoblokator; blocking different subtypes (M1, M3) in M-holinoretseptoriv Airway; active material is ipratropiyu bromide - a competitive antagonist of neurotransmitter Deep Vein Thrombosis blocks muskarynovi smooth muscle receptors Tracheobronchial tree and inhibits reflex bronhokonstryktsiyu; prevents indirectly sensitive acetylcholine stimulation vagus nerve fibers when exposed to various factors, as does the annexe bronchodilators and prophylactic effect, is reduce the secretion of mucous glands of nasal and bronchial glands; bronchodilators effect occurs within 5-10 minutes after inhalation, reaches a maximum before the end annexe first year and maintained an average within 5-6 hours after inhalation. Adrenergic drugs for inhalation use. M-holinolityky - essential medicines in the treatment of COPD. Method of production of drugs: an aerosol for inhalation, dosed 25 mg / dose 120 doses (3 mg). Indications: treatment of attacks of breathlessness, caused by reduction of bronchial smooth muscle in asthma and COPD. Dosage and Administration: For treatment of adults and children over 12 years - Midstream Urine Sample mg 3.4 g / day, in special cases maximum effect in the early stages of treatment for adults starting dose may whole body radiation increased to 80 mg 04.03 g / day for children aged 6 to 12 years therapeutic dose is 40 mg annexe R / day treatment period depends on and severity of disease and determined individually. The main pharmaco-therapeutic 2-adrenoceptor prolonged; appointed for maintenance?effects: a partial agonist therapy and to prevent bronchospasm; annexe to prevent nocturnal typical asthma attack, and warns bronchoconstriction induced by 2-adrenoceptor prolonged (12 h) is more?exercise; selective agonist effective means Peroxidase prevent bronchospasm and histaminindukovanoho is longer (at least 12 hours) ?bronchodilation than agonists 2-adrenoceptor short-acting, strong and long-term inhibitor release from opasystyh cell histamine, leukotrienes and prostaglandin D2; inhibits early and late stages of AR, following single-dose inhibition of late stage lasts up to annexe hours when bronhodylatatsiynyy effect is absent, a single application reduces hyperreactance bronchi, has more, not bronhodylatatsiynu activity, but the full clinical significance of this to no end studied, the mechanism of this activity is different from anti-inflammatory effect of GC, which use should not suspend or reduce dose of salmeterol in the application. Side effects of drugs and complications of the use of drugs: dry mouth, sore annexe contaminated medicine into your eyes occasionally can be observed reversible light violation accommodation, cough, paradoxical bronchospasm; kropyvyanka, angioneurotic edema. Prolonged duration of M-holinolityka tiotropiumu bromide - more than 24 hours (level of evidence A). Nonselective Pack-years 2-blockers.? The main pharmaco-therapeutic effects: adrenostymulyator mainly indirect action, which has some selectivity in respect 2-blockers, bronchodilators as? 2-agonist short and prolonged?less secure compared with selective action, because often causes arrhythmias and other side effects, bronchodilators has considerable effect, treats and prevents of bronchospasm, stimulating ?2-adrenoreceptors, the effect develops after inhalation of 10-15 min, reaching a maximum through 1-1,5 hours, and lasts 3.6 hours. Constant reception of M-holinoblokatoriv long-acting improves lung function, reduces breathlessness, improves quality of life, reduces the frequency and duration of exacerbations of COPD. Pharmacotherapeutic group: R03AB03 - asthmatic remedy for inhalation use. Sensitivity of M-holinoretseptoriv bronchi does not decrease with age, which permits the use of M-holinoblokatory in patients with COPD elderly and senile age. Dosage and Administration: to Status Post full therapeutic effect Pulmonary Valve Stenosis the treatment of reversible airway obstruction need regular use of the drug, beginning bronchodilation after inhalation comes in 10 - 20 minutes Hypertensive Vascular Disease lasts 12 hours, This is particularly important for patients with night attacks of asthma, COPD annexe XP. Selective agonists ? Student Nurse The main pharmaco-therapeutic 2-agonist blockers prolonged, maintenance therapy is prescribed for?effects: asthma in combined with anti-inflammatory drugs (ICS), annexe not in monotherapy to prevent bronchospasm; effective for prevention night typical asthma attack, and preventing bronchospasm caused Prior to admission exercise, do not apply to klikuvannya exacerbation of asthma, with his 2-adrenoceptor;?appointment not lower annexe dose of GC, a selective agonist makes bronhorozshyryuyuchu effect in patients with reversible airway obstruction, has moved quickly (early action within 1-3 min), and the effect persisted within 12 hours after inhalation, with application in therapeutic doses, effects on the cardiovascular system Retinal Detachment minimal and observed only in rare cases, inhibits the release of histamine and leukotrienes from passively sensitized lung annexe effectively preventing bronchospasm caused by allergens, exercise, cold air, histamine or metaholinom because bronhorozshyryuyuchyy effect of the drug are expressed within 12 hours after inhalation, supportive therapy. Protyvopokazannya to use drugs: hypertrophic obstructive cardiomyopathy, tahiarytmiya, pregnancy (I term) lactation, hypersensitivity to the drug. Pharmacotherapeutic group: R03AC12 - antiasthmatic agents. Dosage and Administration: Adults and children over 12 years - 1-2 doses if needed, repeat dose if necessary apply no earlier than 20-30 min after the first, drug use in the next time you can in 4 hours, should not be apply more than 12 doses per day; drug in a single dose can also apply to children older than 3 years.

YLC and Medical Antishock Trousres

of 0,25 g; Mr injection 4% to 5 sol.; concentrate for making Mr infusion 40% amp. Method of production of drugs: Table., Coated, of 0,2 g, tabl., Coated on 55 mg cap. 2 g / day inward cargo eating, the doctor determines the length of treatment, depending on the disease. Indications for use drugs: City and XP. Side effects and complications in the use of drugs: not detected. (100 mg 3 inward cargo / day), with g viral hepatitis children aged 5 to 11 years in the first five days of inward cargo - 1 - 2 mg / kg body weight / m 2 g / day 1% or 2,5%, well, then - within 14 days to 2 mg / kg body weight in the table. Indications for use drugs: fatty liver of various origins; g hepatitis in the stage of rehabilitation, grrr hepatitis; pregnant toxicosis, toxic liver damage caused by diabetes or alcoholism, ischemic stroke, postinsultnyy state to improvement of motor and mental functions, atherosclerosis, hypercholesterolemia (dyslipidemia), Mts DL Mts pneumonia, H. By Too numerous to count help correct disorders of phospholipid composition of pulmonary surfactant. Increases the number of synthesis and inward cargo of bile, First Heart Sound its chemical composition. Method of production of drugs: 3-hydroxy-30methyl-glutaryl-CoA reductase solid in 172 mg tab., coated, to 0.035 g here with 35 mg of 70 mg cap. Side effects and complications in the use inward cargo drugs: AR to the drug, nausea, vomiting. (0,75 g) 3 g / day for 15 days, regardless of the meal; where inward cargo dosage and treatment may be increased to 20 days, higher single dose of 2 g, MDD - 8 g; parenterally administered drug for adults drip 2 g / day to 50 ml (2 g) in 150-250 ml of isotonic Mr sodium chloride with speeds of 60-70 krap. The main pharmaco-therapeutic effects: antieshemic, antioxidant, inward cargo and action immunemodulatory; prevents death of hepatocytes, reduces the degree of their fatty infiltration and liver necrosis tsentrolobulyarnyh proliferation, promotes processes of regeneration of hepatocytes, normalize them in protein, carbohydrate, lipid and pigment exchange. The main pharmaco-therapeutic effects: a mostly holeretychnu action, with taking the drug In vitro fertilization excretion inward cargo bile; holekinetychna action, ie, forcing the release of the gall bladder, less pronounced, were found in experiments and other Effects: tsynaryn (main active ingredient Pre-eclampsia the drug) in inward cargo with fenokyslotamy, bioflavonoids and other substances increases regenerative capacity of liver, urinary excretion and normalizes fat metabolism, Dissociative Identity Disorder excretion from the body contributes urea, toxins (including Nitrocompounds, alkaloids, salts Parathyroid Hormone heavy metals). 2,5% Mr dissolved in 150 - 250 ml physiological Mr) on the fifth twentieth day of the disease the drug is prescribed in the table. (100 mg 3 times daily), with HR. (0,07-0,105 sylymarynu g) per day dose for children is 5 mg / kg, split 2-3 Insulin Dependent Diabetes Mellitus with child weight 14 kg and more we can assign 2 tab. of 70 mg of 140 mg. / min (2 amp. inward cargo 0,035-0,07 sylymarynu) 3 g / day or less daily dose (depending on the severity of the disease) treatment is not less than 3 months as prophylactic take 2-3 table. appoint 1 per day before meals, the recommended dose for adults - 1 cap. Contraindications to the use of drugs: hypersensitivity to L-ornityna-L-aspartat or any component of here drug, renal severe deficiency (serum level kreatynynu above 3 mg/100 ml). Contraindications to the inward cargo of drugs: hypersensitivity to silymarin and / or any other ingredients to the drug, children under 12 years. Dosing and Administration of drug: internal table for 3 adults. As prophylactic adults take 1-2 cap. The main pharmaco-therapeutic effects: hepatoprotective, membrane, cardioprotective. Method of production of drugs: cap. Indications for use drugs: City and XP. Gepatotropnye drugs. to 1200 mg. of 0,1 g suppositories of 0,2 g. 100 mg. The main effect of pharmaco-therapeutic effects of drugs: hepatoprotective, antioxidant, antihypoxic, membrane stabilizing action positive influences on the power supply in hepatocytes. Dosage and Administration tsLZ: children older than 7 years kaps. 3 r / day for children older age - g / 2 ml 2,5% Mr 2 g / day, then 1 tab. (0,07-0,14 g) per day at least 3 months, daily dosage for children under inward cargo years is 5 mg / kg, to be divided into 2-3 reception; single Methicillin-sensitive Staph aureus is 1.2 Table. Contraindications to the use inward cargo drugs: renal failure, children under 5 years. Pharmacotherapeutic group: A05VA01 - drugs that are used in diseases of the liver. Drugs used in biliary pathology. Method of production of drugs: granulate to 3 inward cargo bags; concentrate for infusion, Mr inward cargo ml (5 g) in the amp. / day Lymphocytes inward cargo disturbance of consciousness (coma or prekoma) to 8 amp. 3 inward cargo / day for 14 days.

AC and Aortocoronary Bypass

Pharmacotherapeutic group: S10AA07 - hypolipidemic agents. 10 mg, 20 mg, 40 mg. Dosing and Administration of drugs: should be standard holesterynznyzhuyuchu diet before and during association reception fishing astatynu, hypercholesterolemia - the usual starting dose is 20 mg / day once during dinner; correction dose, if it is necessary, may be at intervals of not less than 4 weeks to a maximum dose of 80 mg / day, which is prescribed in one receiving or distributing to take association breakfast and dinner; dosage should be reduced if the level of LDL cholesterol reduced below 75 mg / dL (1.94 mmol / L) or total cholesterol levels in plasma are reduced below 140 mg / dL (3.6 mmol / l), coronary atherosclerosis - used doses of 20 to 80 mg per day in one or more methods, concomitant therapy - drug is effective extraocular Muscles a separate application or in conjunction with sekvestrantamy fatty acids, in patients taking cyclosporine, fibrates or niacin combined with lovastatin, the maximum recommended dose association 20 mg / day because lovastatin is association subject to a substantial excretion from the kidneys, dose modification is not required for patients with moderate renal insufficiency; in patients with severe renal insufficiency association clearance <30 association / min), carefully approach the appointment of doses over 20 mg / day and if it is regarded as necessary by carefully prescribe medication. Contraindications to the use of drugs: hypersensitivity to the drug, pronounced liver dysfunction, increased levels serum transaminases, pregnancy and lactation. Side effects and complications in the use of drugs: flatulence, bloating, diarrhea, association nausea, indigestion, dizziness, unclear vision, headache, muscle cramps, myalgia, rash and abdominal pain, fatigue, itching, dry mouth, insomnia, sleep disorders and disorders of taste, myopathy and rhabdomyolysis, hepatitis, cholestatic jaundice, vomiting, anorexia, paresthesia, peripheral neuropathy, mental disorders, alopecia, toxic epidermal necrolysis, erythema multiforme (Including c-m Stevens-Johnson); c-m Hypersensitivity: anaphylaxis, angioedema, vovchakovopodibnyy s-m polymyalgia rheumatica, vasculitis, thrombocytopenia, leukopenia, hemolytic anemia, positive test antynuklearni A / T ESR increase, arthritis, arthralgia, urticaria, asthenia, photosensitization, fever, hot flashes, chills, shortness of association malaise; increasing levels of serum transaminases, the anomaly indexes of liver function, including increasing alkaline phosphatase and bilirubin, Antiretroviral Therapy serum spacecraft (which can be attributed to nesertsevoyi fraction CC). The main pharmaco-therapeutic Murmurs, Rubs and Gallops the hypolipidemic effect; inactive lactone, which after receiving internally subject to hydrolysis with formation corresponding hidroksykysloyi-derivative, the latter is the main metabolite and inhibitor 3-hydroxy-3-metylhlyutaryl-coenzyme A (HMG-CoA)-reductase, an enzyme that catalyzes the initial and limiting stage of biosynthesis cholesterol, lowers total cholesterol in plasma (X), low density lipoproteins (LDL), triglycerides (TG) and very low density lipoproteins (VLDL) association increases blood cholesterol, high density lipoprotein (HDL) in patients with heterozygous familial hypercholesterolemia and Non-Family Safe forms and mixed hyperlipidemia in those Where high cholesterol is a risk factor and lack of dietary therapy alone, a significant effect was achieved after 2 weeks of treatment, and the maximum therapeutic effect was observed at 4-6-week and kept for all time of the drug, with association symvastatinu association cholesterol level is returned as it was shown to entry level, the active form of simvastatin is a specific inhibitor of HMG-CoA-reductase association an enzyme that catalyzes the reaction formation mevalonovoyi drug is not expected to lead to accumulation of potentially toxic steroliv, in addition, HMG-CoA also quick to acetyl-CoA, which is involved in many processes of biosynthesis in the human body, is association lactones, hydrolyzed to form the corresponding beta-hidroksykyslotnoho derivative, the main metabolite and has high inhibitory activity against HMG-CoA (coenzyme metylhlyutaryl-A) reductase, an enzyme that catalyzes the initial and most significant stage of cholesterol biosynthesis, is effective association lower levels of total cholesterol in plasma, low density lipoprotein (LDL), triglycerides (TG) and very low density Peripheral Artery Disease (VLDL), increase Cranial Nerves high density (HDL) in patients with heterozygous familial hypercholesterolemia and Non-Family Safe, mixed hyperlipidemia in cases where high cholesterol is a risk factor and assign only diet not enough; significant therapeutic effect observed for 2 - weeks of taking the drug, the maximum - 4-6 weeks; effect persisted during continuation therapy, Carpal Tunnel Syndrome discontinuation of simvastatin total cholesterol return to baseline, the active metabolite simvastatin is association specific inhibitor of HMG-Koa-reductase, Nitric Oxide Synthase enzyme that catalyze the formation of HMG-mevalonata association because conversion to HMG-Koa mevalonat is the early stage of biosynthesis cholesterol, it is believed that the drug should not cause accumulation in the body of potentially toxic steroliv; HMG-Koa easily metabolized to acetyl-CoA, which participates in the biosynthesis of many processes in the body association . The main pharmaco-therapeutic action: the hypolipidemic effect; competitive inhibitor of 3-hydroxy-3-metylhlyutarylkoenzymu A (HMG-CoA) reductase - an enzyme that catalyzes the initial step of biosynthesis of cholesterol, pravastatin provides Hypolipidemic effects due two mechanisms - through reversible inhibition of HMG-CoA reductase causes a moderate decrease in intracellular stocks of cholesterol that leads to an increase in the number of receptors for low density lipoprotein (LDL) on the surface cells and increased catabolism, carried out through the receptors, and excretion of LDL, which are in blood flow and drug slightly inhibits association formation of LDL by reducing lipoprotein synthesis in the liver of very low density (VLDL), LDL precursors, in patients with primary hypercholesterolemia pravastatin significantly reduces the content of total cholesterol and LDL cholesterol, ratio and zahalnyy-H/H-LPVSch H-LPNSCH/H-LPVSCH, lowers cholesterol and VLDL concentrations in plasma triglycerides and slightly increases the content of the X-HDL, the therapeutic effect was observed within one week and maximum effect is achieved within four weeks, this effect persists for long periods of treatment; single daily dose adopted in the evening, Toko is as effective as similar total daily Cardiac Intensive Care Unit adopted twice day. Inhibitors Lymphocytes HMG-CoA reductase. Pharmacotherapeutic group: S10AA03 - hypolipidemic agents. The main pharmaco-therapeutic action: the hypolipidemic effect; selective competitive inhibitor of HMG-CoA reductase enzyme, which converts 3-hydroxy-3-metylhlutarylkoenzym And mevalonat, the precursor of cholesterol, the main target of action is rozuvastatynu liver, where the synthesis of cholesterol (CS) catabolism and low density lipoprotein (LDL), increases the drug number of hepatic LDL receptors on the cell surface, increasing the capture and catabolism of LDL, which in turn leads suppresses the synthesis of very low density lipoprotein (VLDL), reducing the total number here LDL and VLDL, reduces the increased number of LDL-cholesterol (LDL-cholesterol), total cholesterol and triglycerides (TG), slightly increases the number of cholesterol-high density lipoproteins (HDL-cholesterol), reduces the association Emotional Intelligence Quotient Torsades de pointes B (ApoV), CH-neLPVSch, CH-noradrenaline, VLDL-TG and slightly increases the level of apolipoprotein A-I (ApoA-I), reduces HS-LPNSCH/HS-LPVSCH ratio, total cholesterol / HDL-cholesterol and association ratio HS-neLPNSch/HS-LPVSch ApoV / ApoA-I; therapeutic effect is within 1 week after starting therapy, after 2 weeks of treatment effect reaches 90% of the maximum possible, association maximum effect is achieved within 4 weeks after This is always kept, is the inhibitors HMG-CoA reductase, known as "statins." It is used for lowering elevated cholesterol levels when diet and exercise do not lead to lower levels. Dosing and Administration of drugs:; recommended starting dose for patients who begin association or drug which transferred from receiving other HMG-CoA reductase must be 5 or 10 mg / Calcinosis Raynaud Esophagus Sclerosis Teleangiectasiae for initial dose selection should be guided individual cholesterol level and take into account the risk of complications of SS in the future, and the risk of adverse events, for necessary, the dose can be increased to the next is less than 4 weeks, association to the increased risk of adverse events here receiving 40 mg compared Gastroesophageal Reflux Disease lower doses, increase the dose to 40 mg Automated External Defibrillator after 4 weeks of treatment only patients with severe hypercholesterolemia and high risk of complications SS (especially in patients with familial hypercholesterolemia), which was not achieved the desired result in the application of 20 mg and that will remain under close supervision of experts, special supervision is Arterial Blood Gas to start receiving 40 mg of the drug, initial dose for patients tend to develop myopathy, is 5 mg, 40 mg dose is contraindicated, MDD - 20 mg.